Bio/Acc Research by Simone Leonelli
Independent research · biology & adaptive systems

Research hub

Deep reports on fermentation, microbiology, human adaptive systems, and the intersection of culture and biology. Built to be read, cited, and used.

SL
Simone Leonelli
Writer & researcher · Bio/Acc
Fermentation · Anthropology · Microbiology

Fermentation Rituals as Adaptive Protocols

Across time and geography, fermentation repeatedly emerged as a socially governed, materially encoded, microbially executed system for turning seasonal abundance into durable calories, safer food, flavor, ritual meaning, and collective identity. 12 major cross-cultural cases.

Machine/Human · Identity Systems

Music Is Not Taste. It Is Telemetry.

When an AI infers your music taste, it is performing identity compression — mapping your tokens to a latent cultural cluster. This is not recommendation; it is surveillance architecture. A mechanistic breakdown of how AI systems infer identity through cultural surface.

Rite ↯ Recode · Adaptive Systems

From Optimization to Attunement

The optimization paradigm treats the body as a machine to be maximized. Attunement treats it as an organism to be listened to. Ultradian cycles, interoception, and circadian alignment as a design principle — personal, cognitive, technological.

Rite ↯ Recode · Chronobiology

Seasonal Cognition: Four Hormonal Modes of a Year

Spring = dopamine · Summer = serotonin · Autumn = acetylcholine · Winter = melatonin. The brain runs four distinct neurochemical firmware versions per year. Fighting your seasonal mode is the root cause of most productivity problems.

Rite ↯ Recode · Bioelectricity

Bioelectric Rituals × Parallel Minds

Cortisol at dawn. Dopamine pulses. Neural waves weaving through focus and flow. Ancient ritual practices accidentally optimized the bioelectric substrate. A five-phase daily cascade model and three ritual protocols for cognitive synergy.

Machine/Human · Neuroendocrinology

AI × Testosterone: Unlocking Peak Performance

Testosterone is not a gym hormone — it is a systemic optimization signal governing dopaminergic drive, spatial cognition, risk tolerance, and cellular repair. AI tools can now map your hormonal chronotype and design stacks that compound rather than override your biology.

Rite ↯ Recode · Sleep Architecture

Delta Engineering: Designing Your Night to Train Tomorrow's Brain

Your morning mind is compiled the night before. Delta waves (0.5–4 Hz) during slow-wave sleep are the brain's active compilation phase — glymphatic clearance, memory consolidation, GH release. Engineering delta is the highest-ROI cognitive intervention available.

Rite ↯ Recode · Neurophysiology

Brain Waves 101: Delta, Theta, Alpha, Beta, Gamma

Brainwave bands are not states of consciousness — they are operating frequencies, each with distinct functional roles, daily cycles, and hackable entry points. A complete reference with framework table, daily narrative, and three evidence-backed induction protocols.

Rite ↯ Recode · Neuroplasticity

Rewire Your Brain → Rebuild Your Body

Neuroplasticity is mechanistic, not metaphorical — LTP, BDNF, adult hippocampal neurogenesis, cortical remapping. A 14-step protocol organized across four phases: Foundation, Input Quality, Active Rewiring, and Consolidation. From screen-fog to strength.

Bio-Hack // Body-Hack · Circadian Biology

Sunrise as Operating System

The first hour after waking is the most potent pharmacological intervention of your day. Light → cortisol awakening response → dopamine activation. A six-phase morning protocol backed by circadian science, with timing, mechanisms, and dosing for each intervention.

Bio-Hack // Body-Hack · Microbiome Engineering

Ancient Craft to AI Bio-Design: Rewriting Your Gut Health

The gut microbiome produces 90% of the body's serotonin and acts as a second nervous system. Ancient fermentation practices accidentally optimized it. AI can now reverse-engineer those protocols and personalize them to individual microbiome signatures.

Bio-Hack // Body-Hack · Nutritional Pharmacology

EVOO: Your Daily Dose of Edible Biotech

Extra virgin olive oil is a pharmacological agent. Oleocanthal acts as a natural ibuprofen (same COX-1/COX-2 mechanism). Oleic acid drives myelin quality. Polyphenols trigger autophagy. The PREDIMED trial: 30% reduction in cardiovascular events. Six bioactive compounds mapped.

Bio-Hack // Body-Hack · Nutritional Science

Mediterranean Diet: Evidence-Based Biotech You Can Eat

60 years of peer-review distilled into one field guide for heart, brain & gut. The most rigorously validated dietary pattern in nutritional epidemiology — 30–40% cardiovascular mortality reduction, 35% lower Alzheimer's risk, five core molecular pathways explained.

SL

Simone Leonelli

Independent writer and researcher exploring biology, fermentation, microbiology, adaptive systems, and the overlap between human culture and biochemical intelligence. These reports are built for depth — each one attempts to reconstruct a full research picture from primary sources, case studies, and design implications.